top of page
I need a background image for my website that is a laboratory bench, but kinda blurry, but

Reading Is Fundamental

Discoveries don't end when an experiment is finished—they begin when they're shared. We strive to publish rigorous, impactful science while helping every trainee become a thoughtful scientific writer, presenter, and communicator. Our goal is to prepare the next generation of scientists not only to make discoveries, but to tell their stories well.

2026

2025

2024

  • Villanueva Guzman, et al. ACS Infectious Diseases. Rapid Screening to Identify Antivirals against Persistent and Acute Coxsackievirus B3 Infection. 

  • Cruz-Pulido, LoMascolo et al.PLoS Pathogens. Polyamines mediate cellular energetics and lipid metabolism through mitochondrial respiration to facilitate virus replication

  • Tate et al. ACS Infectious Diseases. Peptidomimetic Oligomers Targeting Membrane Phosphatidylserine Exhibit Broad Antiviral Activity

2023

  • Firpo et al. PLoS Pathogens. Polyamines and eIF5A hypusination facilitate SREBP2 synthesis and cholesterol production leading to enhanced enterovirus attachment and infection

  • Mastrodomenico et al. mSphere. Persistent Coxsackievirus B3 infection in pancreatic ductal cells in vitro downregulates cellular polyamine metabolism

  • Marreiros et al. Communications Biology A non-canonical sensing pathway mediates Plasmodium adaptation to amino acid deficiency

  • Cruz-Pulido and Mounce. Seminars in Cellular and Developmental Biology. Good cop, bad cop: Polyamines play both sides in host immunity and viral replication

2022

  • Mastrodomenico et al. ACS Infectious Diseases. Polyamine-Linked Cholesterol Incorporation in Rift Valley Fever Virus Particles Promotes Infectivity

  • LoMascolo et al. Antimicrobial Agents and Chemotherapy. Bisacodyl Limits Chikungunya Virus Replication In Vitro and Is Broadly Antiviral

2021

  • Firpo et al. bioRxiv. Polyamines and eIF5A hypusination facilitate SREBP2 translation and cholesterol synthesis to enhance enterovirus attachment and infection.

  • Hulsebosch et al. bioRxiv. Polyamines mediate enterovirus attachment directly and indirectly through cellular heparan sulfate synthesis

  • Drayman et al. Science. Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2.

  • Hulsebosch et al. Viruses. Polyamine analog diethylnorspermidine restricts Coxsackievirus B3 and is overcome by 2A protease mutation in vitro. 

2020

  • Firpo et al. ACS Infectious Diseases. Targeting polyamines inhibits coronavirus infection by reducing cellular attachment

  • Mastrodomenico et al. ACS Infectious Diseases. Virion-Associated Polyamines Transmit with Bunyaviruses to Maintain Infectivity and Promote Entry

  • Firpo et al. Biomolecules. Diverse functions of polyamines in virus infection

  • Sandler et al. Antimicrobial Agents and Chemotherapy. Novel ionophores active against La Crosse virus identified through rapid antiviral screening

  • López et al. Journal of Virology. High-throughput fluorescence-based screen identifies the neuronal microRNA miR-124 as a positive regulator of alphavirus Minfection

2019

  • ​Tate et al. Cell Reports. Ribavirin induces polyamine depletion via nucleotide depletion to limit virus replication

  • Kicmal et al. Journal of Virology. Polyamine depletion abrogates enterovirus cellular attachment

  • Dial et al. Viruses. Coxsackievirus B3 responses to polyamine depletion via enhancement of 2A and 3C protease activity

  • Mastrodomenico et al. Journal of Virology. Polyamine depletion inhibits bunyavirus infection via generation of noninfectious interfering viruses

The Mounce Lab | Bryan Mounce

Loyola University Chicago
Department of Microbiology and Immunology
Stritch School of Medicine
2160 South First Avenue
Maywood, Illinois

bottom of page